pyPESTO - Parameter EStimation TOolbox for python

Published November 13, 2025 | Version v0.5.7

Software Open

General
- Require Python >=3.11 (#1585)
Documentation
- Updated references and citations (#1601, #1609, #1612)
- Various minor Documentation and Example fixes
Optimization
- update scipy interface (#1588)
Ensemble
- accurate cutoff based on chi2 distribution (#1566)
History
- Add monotonic_history from mutliple histories (#1632)
Profiling
- split ProfilerTask into descending and ascending parts (#1598)
- Profiles nested CIs (#1584)
Visualize
- Fix IndexError in waterfall for all-non-finite values (#1600)
- prettier intervals for profiles by using capstyle (#1607)
- Improve waterfall plot efficiency (#1608)
- remove unnecessary title and axes labels (#1589)
- Nicer pypesto.visualize.profile_cis interval markers (#1626)
- Allow to define colors more flexibly (#1627)
- Prevent invisible plot due to large cluster number in waterfall plot (#1631)
Objective
- Updated roadrunner steady state computation (#1604)

Notes

If you use this software, please cite it using these metadata.

Name	Size	Download all
ICB-DCM/pyPESTO-v0.5.7.zip md5:c43d8a7b7bdc7391e7bb67ed441dec92	1.8 MB	Preview Download

Is supplement to: Software: https://github.com/ICB-DCM/pyPESTO/tree/v0.5.7 (URL)