CORNEAL BIOMECHANICS AND THEIR CLINICAL IMPORTANCE IN KERATOCONUS

Keratoconus is a progressive ectatic disorder characterized by localized thinning and protrusion of the cornea, leading to irregular astigmatism and visual distortion. Recent advances in corneal biomechanics have revolutionized our understanding of its pathogenesis, progression, and treatment strategies. This study aims to evaluate the biomechanical parameters of the cornea—such as corneal hysteresis, corneal resistance factor, and elasticity modulus—and their diagnostic and prognostic significance in patients with keratoconus. By analyzing 150 patients using the Ocular Response Analyzer and Corvis ST, the research highlights early biomechanical changes preceding topographic abnormalities. The results underscore the clinical importance of biomechanical assessment in early detection, risk stratification, and personalized treatment planning, including collagen cross-linking and intracorneal ring segment implantation. Understanding corneal biomechanics provides a foundation for improving outcomes in keratoconus management and reducing the need for corneal transplantation.