A Comprehensive Review on Clerodendrum Serratum: Phytochemistry, Pharmacological Activities and Therapeutic Potential

Clerodendrum serratum  Linn. (Family: Verbenaceae) is very widely distributaed in tropical and subtropical regions of the world. Ethno-medicinal importance of the plant has been reported in various indigenous systems of medicines like Ayurveda, Siddha and Unani for the treatment of various life-threatening diseases such as syphilis, typhoid, cancer, jaundice and hypertension. Somw of the chief constituents found in the plant are D-mannitol, hispidulin, cleroflavone, apigenin, scutellarein, sarratagenic acid, acteoside, verbascoside, oleanolic acid, clerodermic acid, γ-sitosterol,  β-sitosterol, cholestanol, clerosterol, campesterol and 24-ethyl cholesterol. Traditionally, it has been also used as anti-rheumatic, anti-asthmatic, febrifuge, in cephalagia and ophthalmia. The roots of C. serratum are also used as anti-oxidant, anti-bacterial, and anti-fungal. Besides these the anti-microbial value of this herbal plant have been reported in its stems and leaves.The plant use as a vegetable in most of regions of India because of wide range of pharmacological activities. This review is deals with identification, medicinal values, phytochemical and pharmacological action of different part of Clerodendrum Serratum.