EVALUATION OF THE EFFECTIVENESS OF ENZYMATIC TREATMENT IN POSTOPERATIVE COMPLICATIONS WITH PRIMARY CONGENITAL INFANTILE GLAUCOMA

This article is devoted to the study of the effectiveness of enzymatic therapy in the treatment of complications associated with fibrinoid syndrome in the early postoperative period of primary congenital infantile glaucoma. The following methods and materials were used in this study: In the ophthalmology department of the multidisciplinary children’s clinic of Tashkent State Medical University, 16 patients (32 eyes) aged 3 to 10 years with a diagnosis of primary infantile glaucoma were treated. Among the patients, there were 10 boys (62.5%) and 6 girls (37.5%).  All patients underwent surgical intervention. In the early postoperative period, complications such as fibrinoid syndrome developed in some patients. To treat this complication, an enzyme preparation with proteolytic activity (Chymotrypsin 10,000 IU diluted in 4.0 ml of 0.9% sodium chloride solution) was applied to the eyes according to a specific regimen. Patients who developed complications in the early postoperative period were divided into three groups depending on the type of complication:
Group I: 8 patients (16 eyes) with exudative reaction.
Group II: 3 patients (6 eyes) with pigment deposits on the anterior capsule of the lens.
Group III: 5 patients (10 eyes) with hyphema of the anterior chamber.