Published November 4, 2025 | Version v2
Preprint Open

Navigating the Safety Profile of Actinium-225 Targeted Alpha Therapy: A Comprehensive Review

Authors/Creators

  • 1. ROR icon Innsbruck Medical University

Contributors

  • 1. ROR icon Innsbruck Medical University
  • 2. EDMO icon Technical University of Munich

Description

This review aims to collect the available documents on the clinical safety of Ac-225 radiopharmaceuticals targeted alpha radionuclide therapy (TAT) in the literature and summarize practical safety data recommended for clinical development of Ac-225 radiopharmaceuticals.

Files

CTI_Ac-225 Safety 2025.pdf

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Additional details

Funding

European Commission
PRISMAP - The European medical isotope programme: Production of high purity isotopes by mass separation 101008571