Published November 5, 2025
| Version v1
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ADRENERGIC AND CALCIUM REGULATION OF CONTRACTILITY OF NEONATAL RAT CARDIOMYOCYTES IN CULTURE
Authors/Creators
- 1. Institute of Biophysics and Biochemistry
Description
The study demonstrated that activation of the adrenergic system leads to an increase in the frequency of contractions due to stimulation of bisoprolol-sensitive β₁-adrenoreceptors. In addition, neonatal cardiomyocytes demonstrated differential response to the calcium channel antagonist’s verapamil and nifedipine.
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References
- 1. Deng YL, Zhao JY, Yao JH, Tang Q, Zhang L, Zhou HL, Zhang CT, Lv JG, Quan XQ. Verapamil suppresses cardiac alternans and ventricular arrhythmias in acute myocardial ischemia via ryanodine receptor inhibition. Am J Transl Res. 2017 Jun 15;9(6):2712-2722. PMID: 28670363; PMCID: PMC5489875.