Comparative Evaluation of Boenninghausen's and Kent's Repertory in The Management of Chronic Migraine: A Multi-Centric Clinical Study

Background: Chronic migraine is a disabling neurovascular disorder characterized by recurrent headaches and associated systemic symptoms. The individualized homeopathic approach offers significant promise for long-term management, particularly when prescriptions are guided by systematic repertorization. This study compares the clinical outcomes obtained using Boenninghausen’s Therapeutic Pocket Book (T.P.B.) and Kent’s Repertory in patients with chronic migraine.

Objective: To evaluate and compare the therapeutic outcomes of Boenninghausen’s and Kent’s Repertory-based prescriptions in chronic migraine through a multi-centric clinical trial.

Methods: A prospective comparative clinical study was conducted at two centers in Maharashtra—Nashik and Aurangabad—from January to June 2025. A total of 60 patients (30 per group) were enrolled based on ICHD-3 criteria for migraine.

Group A: Boenninghausen’s repertory used for case analysis and prescription.

Group B: Kent’s repertory used for case analysis. Selection of remedies was confirmed through Materia Medica correlation. The primary outcomes included frequency of attacks, intensity (VAS), and Migraine Disability Assessment (MIDAS) score. Data were analyzed using paired t-tests, with p < 0.05 considered statistically significant.

Results: Both groups showed a significant reduction in migraine frequency and intensity after 12 weeks. Mean attack frequency reduced from 6.3 ± 1.2 to 2.8 ± 0.9 in Group A and from 6.1 ± 1.0 to 3.6 ± 1.1 in Group B. MIDAS scores improved by 65% in Group A and 48% in Group B. Remedies frequently indicated were Belladonna, Gelsemium, Natrum muriaticum, and Sanguinaria canadensis.
Conclusion: Boenninghausen’s Repertory proved more effective due to its emphasis on modalities and concomitant symptoms, yielding better individualized prescriptions for chronic migraine management.