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Published October 29, 2025 | Version 8.4.0
Software Open

openmm/openmm: OpenMM 8.4.0

  • 1. Stanford University
  • 2. Iambic Therapeutics
  • 3. Memorial Sloan Kettering Cancer Center
  • 4. QC Ware
  • 5. Toyota Research Institute
  • 6. Chodera Lab // MSKCC
  • 7. Massachussets Institute of Technology
  • 8. NVIDIA
  • 9. Pacific Biosciences of California
  • 10. @Kekulai
  • 11. @StreamHPC
  • 12. @schrodinger
  • 13. Westlake University
  • 14. The University of Iowa
  • 15. ENS de Lyon
  • 16. University of Texas
  • 17. University of Calgary
  • 18. @choderalab & @OpenFreeEnergy
  • 19. @quansight

Description

This release adds lots of new features.

  • QTBIntegrator implements the adaptive quantum thermal bath algorithm. This is a fast method of adding nuclear quantum effects to a simulation.
  • ConstantPotentialForce implements the constant potential algorithm. This is for simulating systems where an electrode is held at a constant potential, for example in capacitors or batteries. At each time step, it automatically solves for the distribution of charges on the electrode.
  • TinkerFiles allows creating systems from Tinker input files (.xyz, .key, .prm).
  • The lipid21 force field is now supported. It is included as part of amber19-all.xml, allowing lipids to be parameterized.
  • OrientationRestraintForce provides a harmonic restraint to prevent molecules or other groups of atoms from rotating.
  • RGForce calculates the radius of gyration of a group of atoms. It is mainly intended for use with CustomCVForce.
  • ForceField will often give better error messages than before, hopefully making it easier to figure out why it couldn't parameterize a system.

Files

openmm/openmm-8.4.0.zip

Files (22.9 MB)

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md5:db52d50a24e94d7ccd7233020107038d
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Additional details

Related works

Is supplement to
Software: https://github.com/openmm/openmm/tree/8.4.0 (URL)

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