THE USE OF BIOCHEMICAL MARKERS IN PSORIASIS: C-REACTIVE PROTEIN, ESR, TNF- α, AND INTERLEUKIN-17

Psoriasis is a skin disease characterized by inflammation and an autoimmune nature. The role of various biochemical markers of inflammation, including C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), and proinflammatory cytokines such as TNF-α and interleukin-17 (IL-17), is currently being actively studied. These markers provide insight into the inflammatory response, the severity of the disease, and can be used to assess the effectiveness of treatment. This article analyzes the role of biochemical markers in the comprehensive assessment of psoriasis, including determining its activity and severity, as well as prognosis and research. Recently, researchers have focused on studying biomarkers such as C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), TNF-α, and interleukin 17 (IL-17), which play a key role in the pathogenesis of inflammation in this disease. Empirical data demonstrating a correlation between increased concentrations of these markers and disease progression are discussed, as well as their application in clinical practice for assessing therapeutic efficacy. The article emphasizes the need for further research to further elucidate the clinical significance of these biomarkers and their integration into personalized psoriasis treatment protocols.