Investigating the Efficacy of Nanoemulsion Formulations Containing Essential Oils Against a Variety of Bacterial Species

The increasing threat of antibiotic resistance necessitates alternative antimicrobial solutions. Essential oils (EOs), particularly rosemary oil, possess potent antibacterial properties but face limitations in solubility and stability. This study investigates the efficacy of nanoemulsions containing rosemary essential oil against Escherichia coli and Klebsiella pneumoniae. Silver nanoparticles were synthesized using green synthesis methods, and the antibacterial activity was assessed via diffusion assays on Mueller Hinton agar. Results indicated a concentration-dependent inhibition, with higher EO concentrations exhibiting stronger antibacterial effects. Klebsiella pneumoniae showed greater susceptibility than E. coli, suggesting potential differences in resistance mechanisms. These findings highlight the promise of EO-based nanoemulsions as alternative antibacterial agents, warranting further research into their mechanisms and applications in antimicrobial therapies.