Published October 26, 2025 | Version v1

The Formulation and Evaluation of Alcohol Based Herbal Hand Sanitizer

Description

The primary goal of this study was to design and evaluate an effective herbal alcohol-based hand sanitizer formulated with natural ingredients that provide both antimicrobial protection and skin-conditioning benefits. Ethanol (70%) served as the main active ingredient due to its well-documented broad-spectrum antibacterial and antiviral properties. To enhance skin compatibility, 5% aloe vera gel was incorporated for its moisturizing, soothing, and healing effects, making the sanitizer suitable for frequent use. Carbopol was used as the gelling agent to attain the desired consistency, while purified water and rose water acted as diluents and imparted a mild, pleasant fragrance. Glycerine functioned as a humectant, helping to retain skin moisture and counteract the drying effect of alcohol. A small quantity of hydrogen peroxide was added to destroy bacterial spores, adhering to WHO formulation standards. Methyl paraben was included as a preservative to improve the product’s stability and ensure microbial safety. The final formulation was evaluated for parameters such as pH, viscosity, spreadability, stability, and antimicrobial activity against common pathogens. Results indicated that the developed hand sanitizer met standard quality parameters, demonstrated strong antibacterial action, and remained gentle on the skin. Overall, the study highlights the potential of this formulation as a natural, safe, and effective alternative to conventional chemical-based hand sanitizers. The final product was subjected to evaluation based on parameters such as pH, viscosity, spread ability, stability, and antimicrobial effectiveness against common pathogenic microorganisms. Findings confirmed that the hand sanitizer conformed to standard requirements and exhibited notable antibacterial properties while being non-irritating and skin-friendly. This study supports the development of a natural, effective, and safe alternative to commercially available chemical-based hand sanitizers.

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115-Review paper-Diksha Kshirsagar.pdf

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