STRUCTURAL AND FUNCTIONAL ALTERATIONS OF LYMPH NODES IN STRESS-RELATED IMMUNODEFICIENCY

Chronic stress disrupts immune homeostasis through neuroendocrine pathways and leads to increased susceptibility to infectious, inflammatory, and autoimmune disorders. Lymph nodes, as the main peripheral immune organs, are directly affected by stress hormones such as glucocorticoids and catecholamines. Identifying histological alterations in lymph nodes is essential for predicting immunodepression and designing prophylactic measures.