Dramatic Velocity Changes Under Temperature Differentials in Ephaptic Tracts

In this note, the authors present the output of in-silico investigations that demonstrate the dependence of ephaptic conduction profiles on the presence of slight temperature variations amongst the axons in a tract. The results show that spurious spikes and altered conduction velocities are created when a temperature gradient is applied. This has implications for our understanding of nerve conduction in non-homeostatic conditions of altered body temperature.