Published October 14, 2025 | Version v1

STRUCTURAL AND ANTIBACTERIAL STUDIES OF THE CONSTITUENTS OF THE ESSENTIAL OIL OF CLEISTOPHOLIS PATENS ENGL. AND DIELS COLLECTED IN GAGNOA (COTE DIVOIRE)

  • 1. Laboratoire De Chimie Bio-Organique Et De Substances Naturelles, UFR Sciences Fondamentales Et Appliquees (UFR SFA), Universite Nangui ABROGOUA, 02 BP 801 Abidjan 02, Cote dIvoire.
  • 2. Laboratoire Des Sciences Et Technologies De lEnvironnement, UFR Environnement, Universite Jean Lorougnon GUEDE, BP 150 Daloa, Cote dIvoire.
  • 3. 2. Laboratoire Des Sciences Et Technologies De l'Environnement, UFR Environnement, Université Jean Lorougnon GUEDE, BP 150 Daloa, Côte d'Ivoire
  • 4. 3. Laboratoire De Constitution De La Matière Et Réactions De Cocody, UFR Sciences Des Structures, De La Matière Et De La Technologie (UFR SSMT), Université Félix HOUPHOUËT-BOIGNY, 01 BP V34 Abidjan 01, Côte d'Ivoire.

Description

The essential oil of Cleistopholis patens (Annonaceae) leaves was obtained by hydrodistillation using a traditional still from leaves collected in the Gagnoa department, Cote dIvoire, with a yield of 0.21%. Chemical analyses were carried out by gas chromatography-mass spectrometry (CPG-MS) and carbon-13 nuclear magnetic resonance (13CNMR). Sixteen compounds, accounting for 95.75% of the total composition, were identified. The chemical profile is characterized by a balanced distribution between hydrocarbon monoterpenes (34.88%) and hydrocarbon sesquiterpenes (36.84%), complemented by oxygenated sesquiterpenes (21.18%) and an aromatic hydrocarbon, naphthalene (5.13%). The major constituents were p-cymene (14.36%), caryophyllene (10.77%), and 3-carene (9.23%). The essential oil of Cleistopholis patens from Gagnoa exhibited pronounced bactericidal activity, attributed to its chemical diversity, notably the presence of compounds well recognized for their effectiveness against a variety of microbial agents.

 

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