MEBioSys
Published October 27, 2025 | Version v1
Dataset Open

Dataset for: Micropatterning and Nanodropletting of Titanium by Shifted Surface Laser Texturing Significantly Enhances In Vitro Osteogenesis of Healthy and Osteoporotic Mesenchymal Stromal Cells

Authors/Creators

  • 1. Experimental Trauma Surgery, Department of Trauma Surgery, University Regensburg Medical Centre, Regensburg, Germany
  • 2. ROR icon University of Würzburg
  • 3. Dalian Medical University, China
  • 4. New Technologies Research Centre, University of West Bohemia, Pilsen, Czech Republic
  • 5. Department of Machining Technology, Faculty of Mechanical Engineering, University of West Bohemia, Czech Republic
  • 6. ROR icon LMU Klinikum
  • 7. Department of Orthopedics and Trauma Surgery, Musculoskeletal University Centre Munich (MUM), Ludwig-Maximilians-University (LMU) Hospital, Munich, Germany
  • 8. Department of Conservative Dentistry and Periodontology, University Hospital Regensburg, Regens-burg, Germany
  • 9. Department of Operative Dentistry and Periodontology, Center for Dental Medicine, Medical Cen-ter—University of Freiburg, Faculty of Medicine, University of Freiburg, Germany
  • 10. Department of Material Science and Metallurgy, University of West Bohemia, Pilsen, Czech Republic
  • 11. ROR icon University Medical Center Freiburg

Description

Data set for experimental paper which is focused on preparation and characterization of titanium scaffolds wchich were subjected to shifted laser surface texturing (sLST) using a nanosecond pulsed laser to create an open pore macrotopography with micro-and nano- Ti droplets. In contrast to conventional laser texturing, which leads to high heat accumulation; in sLST, the frequency of laser pulses is low, allowing for resolidification, thereby creating a surface with abundant coverage micro-/nanodroplets. The main objective was to compare the cellular responses of human mesenchymal stromal cells (hMSCs) on sLST-textured Ti surfaces (LT-Ti) for the first time with standard sand-blasted, acid-etched surfaces (SLA-Ti). In-depth analyses of cell survival, proliferation, shape, mineralization, and gene expression were performed.

Files

data set to publication JFB.zip

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Additional details

Related works

Is derived from
Preprint: 10.5281/zenodo.17338456 (DOI)
Is supplement to
Publication: 10.3390/jfb16110401 (DOI)

Funding

European Union
Operational Programme Johanes Amos Comenius, call Excellent Research, co funded by the European Union, administered by the Ministry of Education, Sports and Youth CZ.02.01.01/00/22_008/0004634
European Union
Project Nr. 349. OSTEOMET: Augmented treatment of osteoporotic bone with innovative organic-inorganic nanoparticle functionalized metal surfaces BYCZ01-349
European Union
Project number: BYCZ01-129: KT-Dent: Cross-border transfer of knowledge in the field of advanced dental materials BYCZ01-129