A Review from Clinical Perspectives of Amniotic Membrane Dressing Vs Other Dressing Methods on Burn Ulcers of Children in Tertiary Healthcare Setups
Authors/Creators
- 1. MBBS, DGO, MRCOG, MRCP (Dublin), FRCS , DM, Mphil, Research Scholar, Department of Regenerative Medicine and Translational Science, School of Tropical Medicine, Kolkata, West Bengal 700073
- 2. M. Sc., M. Phil, Research Scholar, Department of Regenerative Medicine and Translational Science, School of Tropical Medicine, Kolkata, West Bengal 700073
- 3. M.Sc., M. Phil, Research Scholar, Department of Regenerative Medicine and Translational Science, School of Tropical Medicine, Kolkata, West Bengal 700073
- 4. MBBS, MD, MS, D.Sc., FACS, FICS, Former Professor, Department of Regenerative Medicine and Translational Science, School of Tropical Medicine, Kolkata, West Bengal 700073
Description
Abstract
Burn injuries in children represent a significant clinical challenge due to their unique anatomical and
physiological characteristics, including thinner skin, higher risk of fluid imbalance, and greater susceptibility to
infection and scarring. Effective wound management is crucial to promote rapid healing, minimize pain, prevent
complications, and improve long-term functional and aesthetic outcomes. Among the various dressing methods,
amniotic membrane (AM) has emerged as a promising biological dressing due to its rich extracellular matrix,
growth factors, anti-inflammatory properties, and immunological safety. This review critically examines the
clinical perspectives of AM dressing in comparison to conventional and advanced wound dressings, including
silver sulfadiazine, hydrocolloids, and paraffin gauze, in paediatric burn care within tertiary healthcare setups.
Key outcomes, including epithelialization rate, infection control, pain reduction, frequency of dressing changes,
hospital stay, and scar formation, are analyzed to evaluate the effectiveness and practicality of AM in paediatric
populations. The review also addresses challenges related to AM preparation, storage, and application,
highlighting gaps in current research and opportunities for future studies. The evidence suggests that AM
dressing offers significant advantages in paediatric burn management, particularly in enhancing healing
outcomes and patient comfort, and may represent a valuable adjunct or alternative to conventional dressing
methods in tertiary care settings.
Abstract (English)
Abstract
Burn injuries in children represent a significant clinical challenge due to their unique anatomical and
physiological characteristics, including thinner skin, higher risk of fluid imbalance, and greater susceptibility to
infection and scarring. Effective wound management is crucial to promote rapid healing, minimize pain, prevent
complications, and improve long-term functional and aesthetic outcomes. Among the various dressing methods,
amniotic membrane (AM) has emerged as a promising biological dressing due to its rich extracellular matrix,
growth factors, anti-inflammatory properties, and immunological safety. This review critically examines the
clinical perspectives of AM dressing in comparison to conventional and advanced wound dressings, including
silver sulfadiazine, hydrocolloids, and paraffin gauze, in paediatric burn care within tertiary healthcare setups.
Key outcomes, including epithelialization rate, infection control, pain reduction, frequency of dressing changes,
hospital stay, and scar formation, are analyzed to evaluate the effectiveness and practicality of AM in paediatric
populations. The review also addresses challenges related to AM preparation, storage, and application,
highlighting gaps in current research and opportunities for future studies. The evidence suggests that AM
dressing offers significant advantages in paediatric burn management, particularly in enhancing healing
outcomes and patient comfort, and may represent a valuable adjunct or alternative to conventional dressing
methods in tertiary care settings.
Files
IJCPR,Vol17,Issue9,Article26.pdf
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Additional details
Dates
- Accepted
-
2025-08-25