Published October 10, 2025 | Version 1.0
Data paper Open

Disposable electrochemical aptasensor for rapid and selective vancomycin detection in clinical samples: Bridging affinity selection, computational modeling and clinical validation

  • 1. ROR icon Universidad de Oviedo
  • 1. ROR icon Iuliu Hațieganu University of Medicine and Pharmacy
  • 2. ROR icon Universidad de Oviedo

Description

Experimental data to reproduce the studies performed in the article "Disposable electrochemical aptasensor for rapid and selective vancomycin
detection in clinical samples: Bridging affinity selection, computational modeling and clinical validation". It comprises information about the SELEX process (evaluation by UV-VIs spectrometry of the target immobilization efficiency, sequences obtained by cloning-sequencing, thermodynamic parameters of these sequences under the operational conditions, characterization of binding affinity by SPR) and optimization of the aptasensor (immobilization procedure, aptamer concentration, blocking agent immobilization time and concentration and target incubation time), analytical performance (calibration, reproducibility, stability, selectivity) and clinical validation in spiked and clinical serum samples and statistics.

Files

Data Vancomycin aptasensor development.zip

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Additional details

Identifiers

Funding

European Commission
Fish EuTrust 101060712/20-22
Government of Romania
PN-IV-P8-8.1-PRE-HE-ORG-2023- 0076 contract no. 26 PHE/2022
Agencia Estatal de Investigación
PID2021-123183OB-100 MICIN/AEI/10.13039/501100011033
Agencia Estatal de Investigación
Electrobionet RED2022-134120-T
Gobierno del Principado de Asturias
IDE/2024/000677

Dates

Accepted
2025-08-06