Published January 15, 2026 | Version v1.0

Enzyme Engineering Database (EnzEngDB): A Platform for Sharing and Interpreting Sequence-Function Relationships across Protein Engineering Campaigns

  • 1. ROR icon Johns Hopkins University

Description

We developed the Enzyme Engineering Database (EnzEngDB) to provide a centralised resource and an online analysis tool to consolidate sequence-function data from enzyme engineering campaigns, thereby making three contributions: 1) a database into which researchers can deposit public data, 2) visualisation and analysis tools for protein engineers to analyse their own data or compare enzyme variants to other engineering campaigns, and 3) a gold-standard dataset for benchmarking automated extraction. 

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