Published October 3, 2025 | Version 1

Community-Acquired MRSA Causing Liver Abscess in an Immunocompetent Patient

Description

Liver abscesses due to methicillin-resistant Staphylococcus aureus (MRSA) are rare, particularly in immunocompetent individuals. A previously healthy adolescent girl presented with a three-week history of fever and chills. Imaging revealed a right hepatic lobe abscess, and image-guided percutaneous drainage yielded purulent fluid that cultured MRSA. She had no prior hospitalisation, comorbidities, or known risk factors for MRSA. Empirical antibiotics were escalated to intravenous vancomycin based on culture results, followed by oral linezolid. The patient showed significant clinical improvement, and follow-up imaging demonstrated near-complete resolution. This case highlights the need to consider community-acquired MRSA in non-resolving liver abscesses, even in healthy individuals. Early microbiological evaluation remains key to timely and appropriate treatment.

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ICMCRJ-4-1838.pdf

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