A RARE PRESENTATION OF GASTRIC METASTASIS FROM CLEAR CELL RENAL CARCINOMA

Renal cell carcinoma (RCC) is the most prevalent form of kidney cancer and ranks as the 14th most common malignancy worldwide. At the time of diagnosis, around 30% of patients already present with metastatic disease. Bone and visceral metastases are associated with poor prognosis, whereas metastases to endocrine glands tend to have a more favorable outcome. Gastrointestinal metastases (GIMs) are uncommon, and their prognostic significance remains unclear.This report describes an exceptionally rare case of gastric metastasis from clear cell renal cell carcinoma in a 57-year-old female patient managed at the Oncology Department of Hassan II University Hospital in Fes, the patient with no notable past medical history, had been under follow-up since 2016 at the Medical Oncology Department of Hassan II University Hospital in Fes for metastatic clear cell renal cell carcinoma (ccRCC). The primary tumor was located in the left kidney and was initially associated with cutaneous and paravertebral metastases. A systemic treatment with sunitinib, a tyrosine kinase inhibitor, was initiated, leading to stabilization of the disease over a prolonged period.