Published April 19, 2026 | Version v2

Targeted Amplicon Sequencing (Target-seq) Dataset for On- and Off-Target Site Analysis

Description

Dataset for On- and Off-Target Site Analysis

General Information

This dataset contains the raw data from targeted amplicon sequencing (hereafter referred to as Target-seq) experiments designed to analyze the on- and off-target editing events of various base editors. The experiments were conducted in two different cell lines: Human Embryonic Kidney 293T (HEK293T) cells and Hematopoietic Stem and Progenitor Cells (HSPCs). Each dataset corresponds to a specific single guide RNA (sgRNA) targeting a particular genomic locus.

This dataset is organized into eight compressed ZIP archives, each containing tab-separated value (tsv) files with the sequencing results for individual replicates.

Files

README.md

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Additional details

Dates

Available
2026-04-19
Add new data into this repository during our paper revision