Quadrupling the protein family space with global metagenomics

Here you can find the data from the study "Quadrupling the protein family space with global metagenomics".

For Protein Families:

iso_clusters25_names.tsv.bz2

Description: TSV file of isolate clusters with more than 25 members.

Columns: (1)Cluster name (2)Representative isolate protein header (3) Isolate protein member header (4)Isolate protein member sequence

metag_clusters25_names.tsv.bz2

Description: TSV file of metagenomic clusters with more than 25 members.

Columns: (1) Cluster name (2) Representative metagenomic protein header (3) Metagenomic protein member header (4) Metagenomic protein member sequence

For Protein Folds     
structures.tar.gz

Description: Contains three subfolders with protein structure models

1. HQ:High-Quality (pTM ≥ 0.7) models (26,767 pdb files)
2. MQ:Medium-Quality (0.5 ≤ pTM < 0.7) models(47,823 pdb files)
3.  LQ:Low-Quality (pTM < 0.5) models (82,018 pdb files)

foldseek_results.tar.gz

Description: You will find three folders (HQ, MQ & LQ). Each one contains three files: 

1. AF2.tblout (unfiltered hits to AlphaFoldDB)
2. CATH.tblout (unfiltered hits to CATH)
3. PDB.tblout (unfiltered hits to PDB)

NMPFAMSDB2_MODELS_SCORES.txt

Description: A txt file with pTM and pLDDT score for each family model.

Columns:  (1) Family name Column (2) pTm score Column (3)pLDDT score