Phytochemical profiling and cytotoxicity analysis of Vanda tessellata root: an epiphytic orchid of India
Authors/Creators
- 1. Department of Botany, Sidharth Government College, Nadaun, Himachal Pradesh, India
- 2. Department of Chemistry Sahkar Maharshi Bhausaheb Santuji Thorat Arts, Science and Commerce College Sangamner, Ahilyanagar, Maharashtra, India. Affiliated to Savitribai Phule Pune University, Pune, Maharashtra, India
- 3. Department of Botany Shailabala Women's Autonomous College, Cuttack affiliated to Rama Devi women's University, Bhubaneswar, Odisha, India
- 4. Ambika Prasad Research Foundation, Odisha, India
Description
The search for novel therapeutic agents from natural sources has intensified due to the
limitations of conventional drugs and the rise of drug resistance. In this study, the roots of Vanda
tessellata, an epiphytic orchid of India with ethnomedicinal relevance, were subjected to solvent-based
extraction and evaluated for their phytochemical profile and cytotoxic potential. Phytochemical
screening revealed the presence of tannins, alkaloids, reducing sugars, and carbonyl compounds
exclusively in the hydroethanolic extract, while n-hexane and petroleum ether extracts showed no
detectable metabolites. Cytotoxicity analysis using the brine shrimp lethality assay demonstrated 100%
mortality at all tested concentrations for n-hexane and petroleum ether extracts, suggesting potent
cytotoxic effects. In contrast, the hydroethanolic extract exhibited mild toxicity at lower concentrations
and no lethality at higher doses. These findings highlight the solvent-dependent bioactivity of V.
tessellata roots, indicating their potential as a source of novel bioactive compounds for therapeutic
exploration.
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