Chewable Tablets as a Patient-Friendly Drug Delivery System: A Comprehensive Review

Chewable tablets are solid dosage forms that disintegrate slowly when chewed or allowed to dissolve in the mouth for local action. Chewable tablets are especially useful in tablet formulations for children and geriatrics. They offer several advantages over conventional tablets, including improved patient compliance, ease of administration, and enhanced drug bioavailability. The ideal characteristics of a chewable tablet are easy to chew, palatable (masked flavor and taste), and of appropriate size and shape. The Major excipients used in chewable tablets include flavor enhancers and sweeteners and these tablets are Manufactured by Wet granulation, Dry granulation or Direct compression methods. The Evaluation tests for chewable tablets includes chemical and physical methods. Physical methods include appearance, hardness, Friability, disintegration, and dissolution, while chemical methods include assay of drug content, dosage uniformity, in vitro and in vivo testing.