Published August 26, 2025
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A PROSPECTIVE STUDY ON PERITONEAL FLUID CULTURE AND ITS ANTIBIOTIC SENSITIVITY IN PERFORATIVE PERITONITIS PATIENTS
Creators
- 1. Post Graduate Department of General Surgery Alluri Sitaramaraju Academy of Medical Sciences Eluru 524005, Eluru District Andhra Pradesh, India.
- 2. Professor Department of General Surgery Alluri Sitaramaraju Academy of Medical Sciences Eluru 524005, Eluru District Andhra Pradesh, India.
Description
Background: Perforative peritonitis remains a major surgical emergency with high morbidity and mortality. Antibiotic resistance is an emerging challenge.
Methods: A prospective study on 100 patients with hollow viscus perforation was conducted. Peritoneal fluid was collected intraoperatively and subjected to aerobic culture and antibiotic sensitivity using Kirby-Bauer disc diffusion.
Conclusion: Empirical antibiotic therapy should considerhigh resistance to older antibiotics. Culture guided therapy improves outcomes in perforative peritonitis.
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