Published April 30, 2024 | Version v1
Conference proceeding Open

Toxicity of micro- and nanoplastics beyond cytotoxicity : cellular and bioenergetic effects on human cells

Description

In the present study, part of the IMPTOX project, microbiological and toxicological interactions of MNPs and their potential cargo were investigated using state-of-the art methods, such as the Agilent Seahorse XFe96 analyzer and Sartorius SX5 live cell imaging. Using 2D and 3D in vitro cell models with a chronic exposure approach, we gained insights into the potential toxic mechanisms provoked by MNP exposure and the effect of co-exposure of MNPs and contaminants (mycotoxins and cyanotoxins).

Presented at IAFP's European Symposium on Food Safety 2024, Geneva, Switzerland.

This research was conducted in the context of WP6 of the EU Horizon2020 "Imptox" project.

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Additional details

Funding

European Commission
Imptox - AN INNOVATIVE ANALYTICAL PLATFORM TO INVESTIGATE THE EFFECT AND TOXICITY OF MICRO AND NANO PLASTICS COMBINED WITH ENVIRONMENTAL CONTAMINANTS ON THE RISK OF ALLERGIC DISEASE IN PRECLINICAL AND CLINICAL 965173
Research Foundation - Flanders
1506419N
Ghent University
BOF20/BAS/120
FOD Volksgezondheid, Veiligheid van de Voedselketen en Leefmilieu
CYANTIR RT 21/5
Research Foundation - Flanders
G000123N
Ghent University
BOF01P03220