Published 2025 | Version v2

Spatial2GWAS: a database for linking spatial transcriptomic regions with GWAS traits

  • 1. ROR icon The University of Texas Health Science Center
  • 2. ROR icon West China Hospital of Sichuan University
  • 3. ROR icon The University of Texas Health Science Center at Houston

Description

Filename_scdrs_significant_group_table.tar.gz: the spatial region-GWAS trait association analysis results using the scDRS method

Filename_gene_associated_table.tar.gz: genes co-expressed with GWAS  trait-associated genes identified using Pearson's correlation analysis

Filename_drug_target.tar.gz: overlap of genes co-expressed with GWAS  trait-associated genes and drug targets in DGIdb 5.0

Filename_spot_DEGs_table.tar.gz: differentially expressed genes between trait-related and unrelated spots/bins

Filename_region_DEGs_table.tar.gz: differentially expressed genes between trait-related and unrelated spatial regions

Filename_spot_GO_table.tar.gz: enriched GO terms based on differentially expressed genes between trait-related and unrelated spots/bins

Filename_region_GO_table.tar.gz: enriched GO terms based on differentially expressed genes between trait-related and unrelated spatial regions

Filename_spot_KEGG_table.tar.gz: enriched KEGG pathways based on differentially expressed genes between trait-related and unrelated spots/bins

Filename_region_KEGG_table.tar.gz: enriched KEGG pathways based on differentially expressed genes between trait-related and unrelated spatial regions

analysis code.zip: scripts for scDRS pipeline and downstream analysis

Files

analysis code.zip

Files (3.1 GB)

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