Severe GBA1 variants drive the GBA1-PD clinical phenotype: implications for counselling and clinical trials

The 6 files document the code used to perform the statistical analyses detailed in the manuscript "Severe GBA1 variants drive the GBA1-PD clinical phenotype: implications for counselling and clinical trials". 

Code 1: comparison between idiopathic PD and GBA1-PD patients.

Code 1b: comparison between idiopathic PD and GBA1-PD patients, after exclusion of patients with DBS.

Code 2: comparison between idiopathic PD vs risk-GBA1-PD vs mild-GBA1-PD vs severe-GBA1-PD.

Code 2b: data shown in Supplementary Table 4, related to the MOCA subscores for the comparison between idiopathic PD vs risk-GBA1-PD vs mild-GBA1-PD vs severe-GBA1-PD.

Code 2c: data shown in Supplementary Table 6, related to the comparison between idiopathic PD vs risk-GBA1-PD vs mild-GBA1-PD vs severe-GBA1-PD, after exclusion of subjects who underwent DBS.

Code 2d: data shown in Supplementary Table 6, related to the comparison between idiopathic PD vs risk-GBA1-PD vs mild-GBA1-PD vs severe-GBA1-PD, after exclusion of subjects who underwent DBS.

The Key Resource Table (KRT) related to this study is also provided.