Published August 4, 2025 | Version v2

π-HelixNovo2 project: Datasets, codes, model weights, de novo results

Authors/Creators

Description

Supplementary experiments of π-HelixNovo2 project 

Training π-HelixNovo2 on the MassIVE-KB dataset and evaluating it  against π-HelixNovo and Casanovo models trained on the same dataset.

Evaluation was performed on the the nine-species benchmark dataset, the revised nine-species dataset and three antibody datasets, Herceptin (PXD023419), IgG1-Human, and WIgG1-Mouse.

The nine-species benchmark dataset  is available at https://zenodo.org/record/6791263/files/casanovo_preprocessed_data.zip?download=1, the revised nine-species dataset is available at https://zenodo.org/records/12819175/files/nine-species-main.zip?download=1, and three antibody datasets (Herceptin, IgG1-Human, and WIgG1-Mouse) can be available at https://zenodo.org/records/10405582/files/datasets.zip?download=1.

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Evaluation_on_MassIVE-KB_dataset.zip

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