Published July 31, 2025 | Version v1
Journal Open

PIEZO channels link mechanical forces to uterine contractions in parturition (single nuclei RNA-seq)

  • 1. ROR icon Scripps Research Institute

Description

Analysis for single cell RNA-seq data in the study, including the analysis for human, non-pregnant mouse and pregnant mouse uterus.

  1. Human myometrium in labor
    • Request access for data from dbGaP phs001885.v5.p1
    • Download data using the download_data.sh script.
    • Map transcripts using cellranger
    • Analyze the data using the R script
  2. Mouse non-pregnant uterus
    • Download processed matrices from ArrayExpress E-MTAB-11491
    • Analyze the data using the R script
  3. Mouse GD18 uterus
    • Analyze the data from Single Cell Portal (SCP2924)
    • Process the data using the R script

Files

Files (806.4 MB)

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md5:0bb7bff17e77470f819d3f4d17196738
806.4 MB Download

Additional details

Funding

Damon Runyon Cancer Research Foundation
DRG-2405-20
Howard Hughes Medical Institute
National Institutes of Health
R01AT012051
National Institutes of Health
R35 NS105067

Dates

Submitted
2025-08-01