Published July 30, 2025 | Version v1
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PREVALENCE OF METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS IN WOUND INFECTIONS OF PATIENTS ATTENDING SELECTED HOSPITALS IN ESAN CENTRAL, EDO STATE. NIGERIA

Authors/Creators

  • 1. Department of Medical Microbiology, Faculty of Medical Laboratory Sciences, Ambrose Alli University, Ekpoma, Edo State,Nigeria
  • 2. Department of Microbiology, Faculty of Life Sciences, Ambrose Alli University, Ekpoma, Edo State, Nigeria.
  • 3. Department of Community Medicine, Faculty of Clinical Sciences, Ambrose Alli University, Ekpoma, Edo State,Nigeria.

Description

This study investigates the prevalence of Methicillin Resistant
Staphylococcus aureus (MRSA) infection associated with wound patients
from selected hospitals in Esan-Central, Edo State. A total of 152 wound
swabs specimens were collected and analyzed. The study population
comprised 88 males and 64 females. Bacterial isolates were identified using
Gram staining and biochemical tests, including catalase and coagulase;
antibiotic susceptibility tests was done using Kirby Bauer disc diffusion
method. 38 (25%) Staphylococcus aureus isolates were identified, out of
which 31 (81.58%) were methicillin resistant and 7 (18.42%) were
methicillin sensitive. In this study, the overall prevalence of MRSA in
wound infection was 20.39%. The prevalence of MRSA in wound infection
varied insignificantly (p>0.05) with age, with the highest respondents of ≥
70 years old 1 (100%), followed by patients within the age range of 40-
49years old 7 (25.0%), while those within age groups 30-39, ≤19, 60-69, 20-
29 and 50-59 old had prevalence 9 (22.50%), 4 (22.22%), 2 (20.0%), 6
(15.38%), 2 (12.50) respectively MRSA infection amongst male was higher
21 (23.86%) than females 10 (15.63%) although not statistically significant
(p>0.05). There was also no significant variation of MRSA infection based
on occupation, although farmers had the highest prevalence, 9(32.14%)
followed by teachers 6(28.57%). The results suggest the importance and role
of diagnostic clinical microbiology in determining appropriate antimicrobial
therapy thus limiting the emergence and cross transmission of antimicrobial
resistant bacteria and in turn decreased morbidity and mortality.

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Identifiers

ISSN
3049-3013

Related works

Is referenced by
Journal article: 3049-3013 (ISSN)

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