DIABETIS AND PERITONEAL DIALYSIS: LITERATURE REVIEW

Diabetic nephropathy (DNK) is a major health problem associated with an increased risk of morbidity and mortality. Treatment of MRD is challenging given changes in blood glucose homeostasis, unclear accuracy of blood glucose measurements, and altered kinetics of hypoglycemic drugs. There is uncertainty regarding the optimal glycemic target in this population, although recent epidemiological data suggest that HbA1c ranges of 6 8%, as well as 7 9%, are associated with higher survival rates in diabetic patients on dialysis. Furthermore, treatment of diabetes in patients maintained on dialysis is challenging, and many hypoglycemic drugs are metabolized and excreted renally, necessitating dose adjustment or avoidance in dialysis patients. [1] Diabetes, along with vascular disease, is the most common cause of end-stage renal disease (ESRD). Many authors have suggested that continuous ambulatory peritoneal dialysis should be the preferred treatment for diabetics with chronic kidney failure. However, controversy persists regarding the preferred treatment of dialysis in diabetic patients. Currently, the final choice of method will depend on the patient's clinical conditions, preferences, socio-professional environment, the availability of dialysis techniques, the personal beliefs of nephrologists, as well as local facilities and financial considerations. [2]