Published July 18, 2025 | Version v1
Dataset Open

GeoMx Digital Spatial Profiling Data from Human Intestinal Tissue

  • 1. ROR icon Oncode Institute
  • 2. ROR icon Academic Medical Center
  • 3. ROR icon Cancer Center Amsterdam
  • 4. ROR icon Amsterdam University Medical Centers

Description

Description:
This dataset accompanies the manuscript investigating spatial gene expression in human intestinal tissue with dysplasia using NanoString GeoMx Digital Spatial Profiling (DSP). The data includes gene expression measurements and corresponding sample metadata from regions of interest (AOIs) across patient biopsies.

Files Included:
- GeoMx_DSP_data.rds: R serialized object containing the spatial transcriptomics dataset analyzed in this manuscript, including expression and metadata used in analysis (CD14, CEBPB, MPO, OSM, CCL2, ICAM1, IL1B and VEGFA).
- GeoMx_DSP_expression_data.xlsx: Excel file containing the gene expression matrix generated from GeoMx Digital Spatial Profiling (DSP).
- GeoMx_DSP_metadata.xlsx: Excel file providing metadata for each area of interest (AOI), including disease phenotype, patient ID, and sample type.

Files

README_GeoMx_DSP.txt

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