Behavioural assay for olfactory plasticity in C. elegans

C. elegans shows odour adaptation after continuous exposure to an odorant for more than 30 minutes (1). We recently found that odour adaptation is also observed after a short pre-exposure (5 min) to odorants (2). This new type of adaptation requires several interneurons including AIY and RIF, indicating that this behavioural plasticity depends on neural circuits.