Published July 15, 2025
| Version v1
Dataset
Open
Data for Defining the function of disease variants with CRISPR editing and multimodal single cell sequencing: PTEN, FBXO11, HLA-DQB1
Authors/Creators
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1.
Cincinnati Children's Hospital Medical Center
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2.
University of Manchester
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3.
Broad Institute
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4.
Brigham and Women's Hospital
Description
Data corresponds to CRAFTseq, a single-cell assay for sequencing the transcriptome, genomic DNA, and surface markers of CRISPR-edited cells. If interested, our preprint can be found here.
Contents include data corresponding to analysis of cell lines experiments involving PTEN, FBXO11, and HLA-DQB1. Code for analysis of this data can be found on our GitHub.
Files
DQB1_Data_Analysis.zip
Files
(59.2 MB)
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md5:36d9d03808de7cd9827c273a4e790fa2
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Additional details
Software
- Repository URL
- https://github.com/immunogenomics/craft-seq/