Published July 1, 2024 | Version v1

OFFLU Avian Influenza Matching (AIM) Technical Report, July 2024

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This document provides the July 2024 OFFLU Avian Influenza Matching (AIM) Technical Report, produced through the WOAH–FAO network of expertise. It outlines the methodology, reagents, and collaborative framework used to generate harmonised assessments of antigenic characteristics of circulating Gs/Gd-lineage H5Nx viruses. The report explains how chicken antisera, HI assays, and antigenic cartography are applied to compare field strains with vaccine seed strains or surrogates, with the aim of supporting vaccine strain selection, monitoring antigenic drift, and guiding poultry vaccination strategies.

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