Published June 28, 2025
| Version RRSSH - Apr.-May-Jun. 2025
Journal article
Open
Genomic and Biotechnological Investigations of Ocimum sanctum (Tulsi): Unlocking Therapeutic Genes and Metabolic Pathways for Future Drug Development
Authors/Creators
- 1. Research Scholar 'Botany', Faculty of Sciences, Motherhood University, Roorkee
- 2. Supervisor & Professor, Faculty of Sciences, Motherhood University, Roorkee
Description
Ocimum sanctum, known as Tulsi, is a cornerstone of traditional Indian medicine. In recent years,
genomics and biotechnology have provided powerful tools to investigate its therapeutic potential at
the molecular level. This study explores the genomic architecture, gene expression patterns, and
metabolite biosynthesis pathways in Tulsi. Using transcriptomic analysis, molecular docking, and
CRISPR-based metabolic engineering perspectives, we present a comprehensive analysis of key
therapeutic compounds and their biosynthetic gene clusters. The research aims to facilitate the
development of optimized cultivars and bioengineered compounds for pharmaceutical use.