Published June 27, 2025 | Version v1
Dataset Open

Associations between cardiopulmonary fitness and cardiovascular events in survivors of childhood cancer: A report from the St. Jude Lifetime Cohort: de-identified datasets

  • 1. St. Jude Children's Research Hospital
  • 2. ROR icon University of North Texas
  • 3. ROR icon University of Gothenburg
  • 4. ROR icon Sahlgrenska University Hospital
  • 5. EDMO icon University of Memphis
  • 6. ROR icon University of Tennessee Health Science Center

Description

The datasets contain the de-identified data for each anaylsis done for the study published in Medicine and Science in Sport and Excercise entitled: "Associations between cardiopulmonary fitness and cardiovascular events in survivors of childhood cancer: A report from the St. Jude Lifetime Cohort". These data are part of the St. Jude Lifetime cohort. Below is the data dictionary for any variable found wihtin the five datasets:

                                   ID: de-identified, random ID for each participant 

                                   age: age of each participant at evaluation

                                   agedx: age at dianosis of primary neoplasm 

                                   gender: Male or Female

                                   racegrp: Race grouped by definition in the manuscript 

                                   dxgrp:  1 = Acute Lymphoblastic Leukemia; 2 = Acute Myeloid Leukemia; 3 = Other Leukemia; 4 = central nervous system; 5  = Hodgkin Lymphoma 

                                               6 = Non-Hodgkin Lymphoma; 7 = Bone Tumor (Ewings / Osteosarcoma); 8 = Nueroblastoma; 9 = Retinoblastoma; 10 = Soft Tissue sarcoma

                                               11 = Wilms tumor; 12 = Other

                                  aaclassic_any: Any classic alkylating agent recieved; 1 = yes 0 = no

                                  aahvymetal_any: Any heavy metnal alkylating agent recieved; 1= yes 0 = no

                                  anthracyclnes_any: Any anythracyclines recieved; 1= yes 0 = no

                                  corticosteroids_any: Any corticosteroids recieved; 1= yes 0 = no

                                 bleomycin_any: Any bleomycin recieved; 1= yes 0 = no

                                  chestrt_yn: Any radiated that impacted the chest recieved; 1= yes 0 = no

                                  pstatus: Was the observation a participant or non-participant in the study

                                  lowvo2: Categorized vo2 based on their CPET, 1= Low/Below average (< 50%); 0 = above average/high (≥ 50%)

                                pkmets: Peak mets achieved on CPET

                                PA: Did the particpants meet the CDC physical activity guidelines based off the Center for Disease Control’s physical activity 

                                          recommendations of 450 metabolic equivalent hours per week, 1= yes 0 = no

                                smoker:  1=Past; 2=Current; 3=Never
                               
Cardiobase: Baseline cardiopulmonary disease; 1= yes 0 = no

                                 Obesity: Did the participant have a CTCAE grade of 2, 3, or 4; 1= yes, 0 = No

                                 HTN:  Did the participant have a CTCAE grade of 2, 3, or 4; 1= yes, 0 = No

                                 Glucose: Did the participant have a CTCAE grade of 2, 3, or 4; 1= yes, 0 = No

                                   futime: Follow-up time for analysis

                                   d_cardiopulm: Did the participant die from cardiopulmonary disease: 1 = yes 0 = no.

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