Published June 25, 2025 | Version v1
Journal article Open

Canine Mammary Tumors: A Review of Diagnosis, Treatment, and Prognosis

  • 1. Department of Zoology, Qurtuba University of Science and Information Technology Dera Ismail Khan/Peshawar
  • 2. Faculty of Veterinary and Animal Sciences Gomal University Dera Ismail Khan
  • 3. Lecturer ,Department of Small Animal and Clinical Sciences, UVAS Lahore
  • 4. Department of Animal Sciences, University of Sargodha
  • 5. DVM,M.Phil Clinical Medicine & Surgery, Pet Paws Veterinary Clinic, Dammam, Kingdom of Saudi Arabia
  • 6. 2Faculty of Veterinary and Animal Sciences Gomal University Dera Ismail Khan
  • 7. Institute of Microbiology, University of Agriculture, Faisalabad, Pakistan
  • 8. Department of Zoology, Riphah International University, Faisalabad, Punjab, Pakistan
  • 9. Faculty of Veterinary and Animal Sciences, UVAS Lahore

Description

Because of their high incidence and diverse behavior, canine mammary tumors (CMTs) are one of the most commonly diagnosed neoplasms in female dogs and provide a serious health risk. The epidemiological characteristics, pathological categories, clinical manifestations, diagnostic techniques, and therapeutic approaches related to CMTs are described in this review. Age, breed, hormonal state, timing of spaying, and obesity are risk factors for almost half of these tumors, which are malignant. While molecular markers are increasingly used to guide prognosis and therapy selection, histopathology is still the gold standard for diagnosis. The main treatment option is surgical excision, which is frequently complemented by hormone therapy, chemotherapy, and newer immunotherapeutic techniques. The prognosis for malignant cases is still uncertain despite advancements in diagnosis and therapy, which emphasizes the necessity of individualized approaches as well as further research into biomarkers and targeted medicines.

 

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