Virtual Cohort of Four-Chamber Heart Meshes from Atrial Fibrillation Patient CT
Authors/Creators
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1.
King's College London
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2.
Imperial College London
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3.
Medical University of Graz
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4.
Queen Mary University of London
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5.
Guy's and St Thomas' NHS Foundation Trust
- 6. University of Bordeaux
Description
Atrial Fibrillation Patient Heart Meshes
This repository contains four chamber meshes derived from end-diastolic CT scans of 10 atrial fibrillation (AF) patients. The meshes were used in the following publication:
Barrows et al.
"Rhythm control benefits left ventricular function compared with rate control in patients with atrial fibrillation: A computational study."
Heart Rhythm O2, 2025
DOI: https://doi.org/10.1016/j.hroo.2025.04.014
Dataset Contents
Each patient mesh is provided in both VTK and CARP (Cardiac Arrhythmia Research Package) formats, and in pre-processed and post-processed versions.
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.vtk: mesh in VTK format (readable by ParaView, Python, etc.)
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.pts: node coordinates
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.elem: element connectivity
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.lon: fibre directions
Mesh Details
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Source: End-diastolic CT images from 10 AF patients
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Pre-processed versions:
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Include basic anatomical tagging
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Post-processed versions:
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Include clinically relevant features:
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Fibre directions in the atria and ventricles
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Fast endocardial conduction layers (separated as LV, RV and septum)
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Bachmann's bundle
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Atrioventricular isolation surface
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Mesh Region Tags
Each element in the mesh is assigned a numeric tag indicating its anatomical or structural region. The tags are consistent across all meshes.
General Tags (Pre- and Post-Processed Meshes):
| Tag | Description |
|---|---|
| 1 | Left ventricular (LV) myocardium |
| 2 | Right ventricular (RV) myocardium |
| 3 | Left atrial (LA) myocardium |
| 4 | Right atrial (RA) myocardium |
| 5 | Aorta |
| 6 | Pulmonary artery |
| 7 | Mitral valve plane |
| 8 | Tricuspid valve plane |
| 9 | Aortic valve plane |
| 10 | Pulmonary valve plane |
| 11 | Left superior pulmonary vein (LSPV) valve plane |
| 12 | Left inferior pulmonary vein (LIPV) valve plane |
| 13 | Right superior pulmonary vein (RSPV) valve plane |
| 14 | Right inferior pulmonary vein (RIPV) valve plane |
| 15 | Left atrial appendage (LAA) valve plane |
| 16 | Superior vena cava (SVC) valve plane |
| 17 | Inferior vena cava (IVC) valve plane |
| 18 | LAA vein ring |
| 19 | SVC vein ring |
| 20 | IVC vein ring |
| 21 | LSPV vein ring |
| 22 | LIPV vein ring |
| 23 | RSPV vein ring |
| 24 | RIPV vein ring |
Additional Tags in Post-Processed Meshes:
| Tag | Description |
|---|---|
| 25 | Left ventricular Fast Endocardial Conduction layer (LV FEC) |
| 26 | Bachmann’s bundle |
| 27 | Atrioventricular isolation surface |
| 28 | Right ventricular Fast Endocardial Conduction layer (RV FEC) |
| 29 | Septal Fast Endocardial Conduction layer |
Citation
If you use these meshes in your work, please cite:
Barrows RK, Augustin CM, Gsell MAF, Roney CH, Solís Lemus JA, Xu H, Young AA, Rajani R, Whitaker J, Vigmond EJ, Bishop MJ, Plank G, Strocchi M, Niederer SA.
"Rhythm control benefits left ventricular function compared with rate control in patients with atrial fibrillation: A computational study."
Heart Rhythm O2, 2025.
DOI: https://doi.org/10.1016/j.hroo.2025.04.014
Authors
Rosie K. Barrows, Christoph M. Augustin, Matthias A.F. Gsell, Caroline H. Roney, José A. Solís Lemus, Hao Xu, Alistair A. Young, Ronak Rajani, John Whitaker, Edward J. Vigmond, Martin J. Bishop, Gernot Plank, Marina Strocchi, Steven A. Niederer.
This work was completed as part of a PhD supervised by Steven Niederer, Marina Strocchi and Martin Bishop.
Funding
M.S. is supported by the National Institute for Health and Care Research Imperial Biomedical Research Centre and by the British Heart Foundation Centre of Research Excellence (RE/24/130023). S.A.N. acknowledges support from the United Kingdom Engineering and Physical Sciences Research Council (UK EPSRC) (EP/M012492/1, NS/A000049/1, and EP/P01268X/1), the British Heart Foundation (PG/15/91/31812, PG/13/37/30280, SP/18/6/33805), the US National Institutes of Health (NIH R01-HL152256), the European Research Council (ERC PREDICT HF 864055), and the Alan Turing Institute. R.K.B. is supported by the UK EPSRC [EP/T517963/1]. This research was funded in whole or in part by the Austrian Science Fund (10.55776/P37063, 10.55776/I4652 to C.M.A.; 10.55776/I6540 to G.P.). C.M.A. acknowledges support from the US NIH (NIH 1R01HL158667). E.J.V. is supported by the National Research Agency (ANR-10-IAHU-04). For open access purposes, the author has applied a CC BY public copyright license to any author-accepted manuscript version arising from this submission.
Contact
For questions or collaboration requests, please contact:
Rosie Barrows – King’s College London / Imperial College London
Author correspondence:
72 Du Cane Rd,
W12 0NN,
London,
United Kingdom
Email: r.barrows23@imperial.ac.uk