Unveiling the Mystical and Medicinal Significance of Selaginella Bryopteris: A Phytochemical Exploration of the Ramayana's Sanjeevani Booti

Selaginella bryopteris (L.) Baker, commonly known as Sanjeevani booti in the Indian subcontinent, holds a distinguished position at the intersection of mythology and modern phytopharmacology. This review comprehensively examines the phytochemical composition, ethnomedicinal applications, and mythological significance of S. bryopteris with particular reference to its portrayal in the ancient Indian epic, the Ramayana. The pteridophyte's remarkable resilience to desiccation and its ability to revive after apparent death aligns with its legendary depiction as a life-restoring herb. Contemporary scientific investigations have revealed the presence of diverse bioactive compounds including flavonoids, biflavonoids, phenolics, alkaloids, and terpenoids that contribute to its documented antioxidant, anti-inflammatory, antimicrobial, and adaptogenic properties. This article further explores the challenges in conservation of this vulnerable species amidst increasing anthropogenic pressures and climate change, while proposing sustainable cultivation and harvesting approaches. The convergence of traditional knowledge and modern scientific validation of S. bryopteris exemplifies the potential for ancient medicinal texts to guide contemporary drug discovery efforts, particularly in addressing conditions related to oxidative stress, inflammation, and microbial infections.