Multivariate GWAS for ARD
Authors/Creators
Description
This dataset contains genome-wide summary statistics (autosomal variants) computed from a multivariate genome-wide association study of five age-related diseases (heart attack, high cholesterol, hypertension, stroke, and type 2 diabetes) using Genomic Structural Equation Modeling (https://github.com/GenomicSEM/GenomicSEM). The calculated effective sample size is 475,203.
Number of variants: 4,893,454
Column names:
SNP = rsID
CHR = chromosome
BP = base pair location
MAF = minor allele frequency
A1 = effect allele
A2 = other allele
est = effect of the SNP on the common factor
se_c = standard error of the effect
Z_Estimate = est/se_c
Pval_Estimate = corresponding P-value of Z_Estimate
Q = heterogeneity estimate of the SNP
Q_df = degree of freedom for Q
Q_pval = P-value associated with the Q statistics
Files
Files
(328.2 MB)
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md5:8aa9e1cd6f25053d45059684a040a337
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328.2 MB | Download |