Published November 24, 2025 | Version v2
Dataset Open

A Diffusion-Based Framework for Designing Molecules in Flexible Protein Pockets

Authors/Creators

Description

Datasets for the paper: A Diffusion-Based Framework for Designing Molecules in Flexible Protein Pockets

moad.ckpt: the checkpoint file of the model trained on Binding MOAD dataset.

yuel_design.zip: source codes of YuelDesign

every_part_a.zip, every_part_b.zip: The Binding MOAD dataset.

cdk2_yueldesign.tar: the molecules generated by YuelDesign for CDK2.

cdk2_diffsbdd: the molecules generated by DiffSBDD for CDK2.

cdk2_pmdm: the molecules generated by PMDM for CDK2.

cdk2_pocket.pdb: the pocket file of CDK2.

cdk2_ref.sdf: the reference ligand file used for molecule generated with DiffSBDD.

Files

every_part_a.zip

Files (6.3 GB)

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