Barking Up the Right Tree: RNA-seq Data for Immune Checkpoint Study in Humans and Dogs

This archive contains input data and processed objects associated with the RNA-seq analysis described in:

Barking Up the Right Tree: Immune Checkpoint Signatures of Human and Dog Cancers
Preprint: https://doi.org/10.1101/2024.06.26.600825  (currently in review at PLOS Computational Biology)

Structure:
- INPUT/: All raw and filtered input files used in the R analysis (.tsv from Kallisto, .gtf annotation, filtered data and metadata tables)
- OUTPUT/: DESeq2-processed object (`BarkingUpTree_DDS_processed.RData`) used to generate figures and tables

For corresponding code and instructions, see the GitHub repository:  
https://github.com/MikolajKocikowski/BarkingUpTree-ploscb

The original raw datasets analyzed in this project are described and cited in the associated manuscript.