Published May 19, 2025 | Version v1
Dataset Open

NIH Roadmap Epigenomics Mapping Consortium Data

  • 1. ROR icon National Institutes of Health

Description

NIH Roadmap Epigenomics Mapping Consortium Data
 
Data presented here are from the following publication:
 
Kundaje*, Meuleman*, Ernst*, Bilenky* et al. Integrative analysis of 111 reference human epigenomes. Nature 518, 317–330 (2015). https://doi.org/10.1038/nature14248
 
 
  • DNA methylation data are available at: roadmap.dnam.tar.gz
             These data were downloaded from https://egg2.wustl.edu/roadmap/data/byDataType/dnamethylation/
 
  • Chromatin states, core 15-state model (5 marks, 127 epigenomes) are available at: roadmap.chmm.tar.gz
             These data were downloaded from https://egg2.wustl.edu/roadmap/data/byFileType/chromhmmSegmentations/ChmmModels/coreMarks/jointModel/final/
 
  • DNase-seq and ChIP-seq peaks are available in several modalities:
             -consolidated data: roadmap.peaks.consolidated.tar.gz
                          These data were downloaded from https://egg2.wustl.edu/roadmap/data/byFileType/peaks/consolidated
 
             -unconsolidated data: given file size limits, these were separated into broad, gapped and narrow peak format:
 
                          -broadPeak: roadmap.peaks.unconsolidated.broadPeak.tar.gz
                                       These data were downloaded from https://egg2.wustl.edu/roadmap/data/byFileType/peaks/unconsolidated/broadPeak
 
                          -gappedPeak: roadmap.peaks.unconsolidated.gappedPeak.tar.gz
                                       These data were downloaded from https://egg2.wustl.edu/roadmap/data/byFileType/peaks/unconsolidated/gappedPeak
 
                          -narrowPeak: roadmap.peaks.unconsolidated.narrowPeak.tar.gz
                                       These data were downloaded from https://egg2.wustl.edu/roadmap/data/byFileType/peaks/unconsolidated/narrowPeak

 

Addendum:

  • RNA data can be found at https://zenodo.org/uploads/15465494
  • Consolidated Imputed peaks can be found at https://zenodo.org/uploads/15465558

Files

Files (199.3 GB)

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md5:172e0c5c7ef4b8c9083eff10601c46f9
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Additional details

Related works

Is continued by
Dataset: https://zenodo.org/uploads/15465494 (URL)
Dataset: https://zenodo.org/uploads/15465558 (URL)
Is described by
Publication: 10.1038/nature14248 (DOI)