STI1 domain engages transient helices to mediate Dsk2 phase separation and proteasome condensation

Simulation Data for: STI1 domain engages transient helices to mediate Dsk2 phase separation and proteasome condensation

Authors: Nirbhik Acharya, Emily A. Daniel, Thuy P. Dao, Erin Mulvey, Jessica K. Niblo, Shahar Sukenik, Daniel A. Kraut, Jeroen Roelofs, Carlos A. Castañeda

This repository contains the trajectory data from molecular dynamics simulations included in "STI1 domain dynamically engages transient helices in disordered regions to drive self-association and phase separation of yeast ubiquilin Dsk2". Simulations were performed using CALVADOS3COM. Trajectory files are in .dcd format and come with an accompanying topology pdb file. 

File description: 

• WT_bound.tar.gz contains all trajectory data for full length Dsk2 in the bound conformation 
• WT_unbound.tar.gz contains all trajectory data for full length Dsk2 in the unbound conformation 

See analysis repository at: https://github.com/sukeniklab/Dsk2_transient_helices