MGSSdouglas/snATAC_MDD: snATAC_MDD

This repository contains a comprehensive set of scripts designed to facilitate the analysis of single-nucleus Assay for Transposase-Accessible Chromatin sequencing (snATAC-seq) data derived from post-mortem human brain tissues of MDD and neurotypical subjects. The provided workflows include preprocessing, quality control, peak calling, clustering, cell-type annotation, differential chromatin accessibility analysis, and gapped kmer SVM for causal variant identification