Surgery
Published September 1, 2022 | Version v1
Journal article Open

Malignant proliferating trichilemmal tumor in the inguinofemoral region in a 33-year-old male – a rare clinical case

Authors/Creators

  • 1. Medical Institute of the Ministry of Interior

Description

Malignant proliferating trichilemmal tumors of the skin (MPTTS) are very rare oncological disease with origin from the adnexal structures of the skin - from the outer root sheath of the hair follicles. The benign variant – trichilemmal cysts – are more common, and in extremely rare cases they can degenerate into a malignant. The most common localization is the scalp area, less often - in the neck area, limbs and groin.An accurate histological diagnosis is very important. The main imaging methods are CT, MRI and PET-CT. Surgery is the only radical treatment providing longterm survival and good results.
We present a rare clinical case of a young man with a malignant proliferating trichilemmal tumor in the inguino-femoral region.

Abstract (Bulgarian)

Злокачествените пролиферативни трихилемални тумори на кожата (ЗПТТК) са много редки онкологични заболявания, произхождащи от аднексите на кожата - от външната коренова обвивка на космените фоликули.
По-често се среща доброкачественият вариант – трихилемални кисти и в изключително редки случаи те могат да дегенерират злокачествено. Срещат се предимно в областта на скалпа, по-рядко – в областта на врата, крайниците и слабините. Изключително важно е поставянето на точна хистологична диагноза. 
Основни методи за диагностика са КАТ, ЯМР и ПЕТ-КТ. Хирургията е основното радикално лечение, осигуряващо дългосрочна преживяемост и добри резултати.
Представяме рядък клиничен случай на млад мъж със злокачествен пролиферативен трихи- лемален тумор в ингвино-феморалната област.

Files

v86i3-5.pdf

Files (2.7 MB)

Name Size
md5:5b5c4d4d631ea7612788a841545a6465
2.7 MB Preview Download

Additional details

Additional titles

Translated title (Bulgarian)
Злокачествен пролиферативен трихилемален тумор в ингвино-феморалната област при 33 годишен мъж – рядък клиничен случай

Identifiers

ISSN
3033-151X
URL
https://bgss.eu/index.php/surgery/article/view/27

Dates

Issued
2022-09-01

References

  • 1. Goyal S, Jain BB, Jana S, Bhattacharya SK. Malignant proliferating trichilemmal tumor. Indian J Dermatol. 2012 Jan;57(1):50-2. PMID: 22470211; PMCID: PMC3312659. https://doi.org/10.4103/0019-5154.92679
  • 2. Jones EW. Proliferating epidermoid cysts. Arch Dermatol. 1966 Jul;94(1):11-9, PMID: 5938217.
  • 3. Kim HJ, Kim TS, Lee KH, Kim YM, Suh CH. Proliferating trichilemmal tumors: CT and MR imaging findings in two cases, one with malignant transformation. AJNR Am J Neuroradiol. 2001 Jan;22(1):180-3. PMID: 11158906; PMCID: PMC7975556.
  • 4. Laing V, Knipe RC, Flowers FP, Stoer CB, Ramos-Caro FA. Proliferatingtrichilemmal tumor: report of a case and review of the literature. J Dermatol Surg Oncol. 1991 Mar;17(3):295-8. PMID: 2005253. https://doi.org/10.1111/j.1524-4725.1991.tb03646.x
  • 5. Leyendecker, Pierre; de Cambourg, Ghislaine; Mahé, Antoine; Imperiale, Alessio; Blondet, Cyrille. 18F-FDG PET/CT Findings in a Patient With a Proliferating Trichilemmal Cyst. Clinical Nuclear Medicine: July 2015 - Volume 40 - Issue 7 - p 598-599 https://doi.org/10.1097/RLU.0000000000000742.
  • 6. López-Ríos F, Rodríguez-Peralto JL, Aguilar A, Hernández L, Gallego M. Proliferating trichilemmal cyst with focal invasion: report of a case and a review of the literature. Am J Dermatopathol. 2000 Apr;22(2):183-7. PMID: 10770443). https://doi.org/10.1097/00000372-200004000-00018
  • 7. Markal N, Kurtay A, Velidedeoğlu H, Hücümenoğlu S. Malignant transformation of a giant proliferating trichilemmal tumor of the scalp: patient report and literature review. Ann Plast Surg. 1998 Sep;41(3):314-6. PMID: 9746092. https://doi.org/10.1097/00000637-199809000-00017
  • 8. Satyaprakash, Anita K.; Sheehan, Daniel J.; Sangüeza, Omar P. Proliferating Trichilemmal Tumors: A Review of the Literature. Dermatologic Surgery: September 2007 - Volume 33 - Issue 9 - p 1102-1108, PMID: 17760602; https://doi.org/10.1111/j.1524-4725.2007.33225.x
  • 9. Sau P, Graham JH, Helwig EB. Proliferating epithelial cysts. Clinicopathological analysis of 96 cases. J Cutan Pathol. 1995 Oct;22(5):394-406. PMID: 859407. https://doi.org/10.1111/j.1600-0560.1995.tb00754.x
  • 10. Wang Guojie, Zhou Xuan, Luo Junqi, Hu Qiyi, Zhang Jie, Case report: Malignant proliferating trichilemmal tumor of the thumb, Frontiers in Oncology, VOL12, 2022, ISSN 2234-943X, https://doi.org/10.3389/fonc.2022.1005206 11. Weiss J, Heine M, Grimmel M, Jung EG. Malignant proliferating trichilemmal cyst. J Am Acad Dermatol. 1995 May;32(5 Pt 2):870-3., PMID: 7722047. https://doi.org/10.1016/0190-9622(95)91550-8