PRP: Pathogenic Risk Prediction for Rare Nonsynonymous Single Nucleotide Variants

This repository contains the training dataset and three independent test datasets used in the study "PRP:Pathogenic Risk Prediction for Rare Nonsynonymous Single Nucleotide Variants."

Each file includes the following columns:

• chr: chromosome

• pos: genomic position

• alRef: Reference allele

• alAlt: Alternative allele

• aaRef: Reference amino acid

• aaAlt: Altered amino acid

• clnSig: Clinical significance of the variant (pathogenic=1, benign=0)