This repository contains a dataset supporting results reported in: 

Overview

In this study, healthy subjects received cortico-cortical paired associative stimulation (ccPAS) under four different µ-phase conditions targeting the left (conditioning) M1 and right (test) M1: trough-trough, trough-positive peak, positive peak-trough, and random phase. Short interhemispheric inhibition (SIHI) and resting-state EEG were recorded before and after the intervention. Further details are provided in the associated publication.

The dataset is intended for use with the code available at: https://github.com/mariaermolova/M1M1PAS

Dataset Structure

1. SIHIdata.csv

Single-trial conditioned MEP amplitudes elicited by paired-pulse stimulation. MEP amplitudes are normalized by (i.e., divided by) the average unconditioned MEP amplitude from the same recording. MEP amplitudes from the conditioning site (FDIr and APBr) are also given.

Columns:

• Subject: Subject ID

• Intervention: Phase-targeting condition

• Time: Time of measurement relative to intervention

• Channel: EMG channel (muscle)

• Intensity: Conditioning pulse intensity (%MSO)

• Response: Conditioned MEP amplitude, normalized

Labels:

• Intervention types:

  • negneg = trough-trough

  • negpos = trough-positive peak

  • posneg = positive peak-trough

  • random = random phase

• Time points:

  • Pre = pre-intervention

  • 0 = immediately post-intervention

  • 30 = 30 minutes post-intervention

  • 60 = 60 minutes post-intervention

• Channels:

  • FDIr = First Dorsal Interosseous (right hand, conditioning site)

  • ABPr = Abductor Pollicis Brevis (right hand)

  • FDIl = First Dorsal Interosseous (left hand, conditioned/test site)

  • APBl = Abductor Pollicis Brevis (left hand)

2. MEPdataPP.csv

Same structure as SIHIdata.csv, but MEP amplitudes are not normalized (i.e., raw conditioned MEP amplitudes, in µV).

3. MEPdataSP.csv

Same structure as SIHIdata.csv. Single-trial unconditioned MEP amplitudes, elicited by single-pulse stimulation of the test site (in µV).

4. sourceConnectivity.csv

Single-epoch alpha-band wPLI values from resting-state EEG.

Columns:

• Subject: Subject ID

• Intervention: Intervention type

• Time: Time of measurement

• wpli: Weighted Phase Lag Index (wPLI) value

Labels:

• Run numbers:

  • 1 = First pre-intervention recording

  • 2 = Second pre-intervention recording

  • 3 = 0 min post-intervention

  • 4 = 30 min post-intervention

  • 5 = 60 min post-intervention

5. sourcePhLag.csv

Same structure as sourceConnectivity.csv. Instantaneous phase lags between right and left M1 alpha-band signals from resting-state EEG.

Columns:

• Subject: Subject ID

• Intervention: Intervention type

• Time: Time of measurement

• Phase_lag: Instantaneous phase lag (in radians)

Notes

• In the EMG recordings, the right hand corresponds to the conditioning hemisphere (left M1 stimulation), and the left hand corresponds to the conditioned/test hemisphere (right M1 stimulation).

• In sourceConnectivity.csv, the first baseline (Time = 1) was removed in some analyses to match available SIHI data.